Jean Powers Selected Research

OGX-011

9/2010	Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer.
1/2009	Phase II trial of OGX-011 in combination with docetaxel in metastatic breast cancer.
2/2008	A phase I study of OGX-011, a 2'-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer.
9/2005	A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jean Powers Research Topics

Disease

10	Neoplasms (Cancer) 01/2019 - 05/2005
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2017 - 04/2008
4	Fatigue 02/2009 - 04/2005
3	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 09/2005
3	Anorexia 02/2009 - 04/2005
2	Hypersensitivity (Allergy) 01/2019 - 09/2015
2	Neutropenia 01/2019 - 04/2005
2	Diarrhea 09/2015 - 02/2009
2	Disease Progression 09/2015 - 05/2003
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 03/2011 - 05/2003
2	Fever (Fevers) 09/2010 - 02/2008
2	Waldenstrom Macroglobulinemia (Macroglobulinemia) 03/2009 - 04/2007
2	Nausea 05/2005 - 04/2005
1	Stomatitis 01/2019
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2019
1	Multiple Myeloma 01/2016
1	Glioblastoma (Glioblastoma Multiforme) 09/2015
1	Venous Thromboembolism 09/2015
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2014
1	Hyperglycemia 03/2014
1	Lymphatic Metastasis 09/2010
1	Lymphoma (Lymphomas) 03/2009
1	Colorectal Neoplasms (Colorectal Cancer) 02/2009
1	Hypertension (High Blood Pressure) 02/2009
1	Breast Neoplasms (Breast Cancer) 01/2009
1	Hemorrhage 04/2008
1	Alopecia (Baldness) 02/2008
1	Lung Neoplasms (Lung Cancer) 02/2008
1	Chills 02/2008
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2007
1	Lethargy 10/2005
1	Myocardial Infarction 10/2005
1	Cardiotoxicity 10/2005
1	Thrombocytopenia 1 10/2005
1	Muscle Weakness 05/2005
1	Confusion (Bewilderment) 05/2005
1	Dyspnea (Shortness of Breath) 05/2005
1	Headache (Headaches) 05/2005
1	Dehydration (Water Stress) 05/2005
1	Transitional Cell Carcinoma 05/2005
1	Glioma (Gliomas) 04/2005

Drug/Important Bio-Agent (IBA)

4	OGX-011IBA 09/2010 - 09/2005
4	Pharmaceutical PreparationsIBA 04/2008 - 04/2005
3	Bortezomib (Velcade)FDA Link 03/2011 - 04/2007
3	Docetaxel (Taxotere)FDA Link 09/2010 - 02/2008
3	ClusterinIBA 09/2010 - 09/2005
3	cediranib (AZD2171)IBA 03/2009 - 04/2008
2	PX-866IBA 01/2019 - 09/2015
2	Cisplatin (Platino)FDA LinkGeneric 03/2014 - 03/2009
2	Gemcitabine FDA Link 03/2011 - 03/2009
2	Tyrosine (L-Tyrosine)FDA Link 03/2009 - 04/2008
2	Phosphotransferases (Kinase)IBA 03/2009 - 04/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2009 - 04/2008
1	Vinca AlkaloidsIBA 01/2019
1	temsirolimus FDA Link 01/2019
1	MTOR InhibitorsIBA 01/2019
1	Vinblastine (Vinblastine Sulfate)FDA Link 01/2019
1	TOR Serine-Threonine KinasesIBA 01/2019
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 09/2017
1	GSK 1363089IBA 09/2017
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2017
1	1- cyclopropyl- 3- (3- (5- morpholin- 4- ylmethyl- 1H- benzoimidazol- 2- yl)- 1H- pyrazol- 4- yl)ureaIBA 01/2016
1	Aurora KinasesIBA 01/2016
1	EnzymesIBA 09/2015
1	Etoposide (VP 16)FDA LinkGeneric 03/2014
1	Somatomedin Receptors (Somatomedin Receptor)IBA 03/2014
1	dalotuzumabIBA 03/2014
1	Prednisone (Sone)FDA LinkGeneric 09/2010
1	Proteasome InhibitorsIBA 03/2009
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 02/2009
1	Fluorouracil (Carac)FDA LinkGeneric 02/2009
1	Angiogenesis InhibitorsIBA 01/2009
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2008
1	Carboplatin (JM8)FDA LinkGeneric 04/2008
1	TroponinIBA 10/2005
1	T 900607 (T900607)IBA 10/2005
1	AT 130IBA 10/2005
1	AndrogensIBA 09/2005
1	Antisense OligonucleotidesIBA 09/2005
1	lonafarnib (SCH 66336)IBA 05/2005
1	AntidiarrhealsIBA 05/2003
1	alvocidib (flavopiridol)IBA 05/2003

Therapy/Procedure

5	Drug Therapy (Chemotherapy) 03/2014 - 02/2008
2	Castration 01/2019 - 09/2010
2	Therapeutics 01/2019 - 09/2015
1	Combination Drug Therapy (Combination Chemotherapy) 03/2009
1	Drug Tapering 04/2007
1	Intravenous Infusions 09/2005
1	Prostatectomy (Retropubic Prostatectomy) 09/2005
1	Adjuvant Chemotherapy 04/2005